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AROTEC Autoantigen Standards
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> Published research papers & AROTEC
Published research papers & AROTEC
New Zealand Origin material
AROTEC Autoantigen Standards
Published research papers & AROTEC
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(Applies to papers or posters published after 2015)
(2020) Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity. J Immunol.
(2019) Label-free electrochemical impedimetric immunosensor for sensitive detection of IgM rheumatoid factor in human serum. Biosens Bioelectron
(2019) Macrophage Migration Inhibitory Factor Regulates U1 Small Nuclear RNP Immune Complex-Mediated Activation of the NLRP3 Inflammasome. Arthritis Rheumatol.
(2019) Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sjögren's syndrome. Autoimmunity
(2019) Functional Characterization of CD11c+ Age-Associated B Cells as Memory B Cells. J Immunol.
(2019) Differences in Self-Recognition between Secreted Antibody and Membrane-Bound B Cell Antigen Receptor. J Immunol.
(2019) High TLR7 Expression Drives the Expansion of CD19+CD24
Transitional B Cells and Autoantibody Production in SLE Patients. Front Immunol.
(2019) Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcγRIIA-Dependent but TLR-Independent Response. J Immunol.
(2018) Immune tolerance to apoptotic self is mediated primarily by regulatory B1a Cells. Front. Immunol.
(2018) Detection of autoantibodies to the p200-epitope of SSA/Ro52 antigen. A comparison of two laboratory assays. Clin Chem Lab Med.
(2018) TACI deletion protects against progressive murine lupus nephritis induced by BAFF overexpression. Kidney Int. 94(4):728-740
(2018) Galectin-3 deficiency drives lupus-like disease by promoting spontaneous germinal centers formation via IFN-γ. Nat Commun.
(2018) Precipitating anti-dsDNA peptide repertoires in lupus. Clin Exp Immunol.
(2018) Mechanisms of Pathogenic Effects of Eosinophil Cationic Protein and Eosinophil Derived Neurotoxin on Human Keratinocytes. Exp Dermatol.
(2018) MiR-155 controls follicular Treg cell-mediated humoral autoimmune intestinal injury by inhibiting CTLA-4 expression. Int Immunopharmacol.
(2017) DOCK8 regulates fitness and function of regulatory T cells through modulation of IL-2 signaling. JCI Insight.
(2017) TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA. J Exp Med. 214(7):2103-2119
(2017) Ro52 autoantibodies arise from self-reactive progenitors in a mother of a child with neonatal lupus. J Autoimmun. 79:99-104
(2017) Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis. Ann Rheum Dis. 76(7):1176-1183
(2017) Relevance of CD6-Mediated Interactions in the Regulation of Peripheral T-Cell Responses and Tolerance. Front Immunol. 8:594
(2017) Oxidized Hemoglobin Is Antigenic and Immunogenic in Lupus. Front Immunol. 8:732
(2017) Photonic ring resonance is a versatile platform for performing multiplex immunoassays in real time. J Immunol Methods. 448:34-43
(2017) The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire. J Immunol. 10.4049
(2017) Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease. Clin. Immunol.
(2017) B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity. J Exp. Med.
(2017) Innate and humoral recognition of the products of cell death: differential antigenicity and immunogenicity in lupus. Clin Exp Immunol. 187(3):353-368
(2016) Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users. PLoS One. 11(7):e0158641
(2016) Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells. Methods Mol Biol. 1390:249-72
(2016) Elucidation of the potential disease-promoting influence of IgM apoptotic cell-reactive antibodies in lupus. Lupus.
Al Kindi MA
(2016) Secreted autoantibody repertoires in Sjögren's syndrome and systemic lupus erythematosus: A proteomic approach. Autoimmun Rev. S1568-9972(16)30001-5
(2016) Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like diseases. Nat Med. 22(2):146-53
(2016) C1q Modulates the Response to TLR7 Stimulation by Pristane-Primed Macrophages: Implications for Pristane-Induced Lupus. J Immunol. 125(4):1488-94
Al Kindi MA
(2016) Lupus anti-ribosomal P autoantibody proteomes express convergent biclonal signatures. Clin Exp Immunol. 184(1):29-35
(2016) IgV peptide mapping of native Ro60 autoantibody proteomes in primary Sjögren's syndrome reveals molecular markers of Ro/La diversification. Clin Immunol. S1521-6616(16)30359
(2016) Targeting downstream transcription factors and epigenetic modifications following Toll-like receptor 7/8 ligation to forestall tissue injury in anti-Ro60 associated heart block. J Autoimmun. 67:36-45
(2016) A novel sol particle immunoassay for fecal calprotectin in inflammatory bowel disease patients. Clin Chem Acta. 1;456:1-6
(2016) Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers. Arthritis Res Ther. 18(1):111
(2016) CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP. JEM. October 17, 2016 Volume 213, No. 11
(2016) Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis. J Immunol. 197(1):27-41
(2016) Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity. Immunity. 44(6):1350-64
(2016) Self-reactive IgE exacerbates interferon responses associated with autoimmunity. Nat Immunol. 17(2): 196-203
(2016) B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. J Exp Med. 213(5):733-50
(2016) Treg17 cells are programmed by Stat3 to suppress Th17 responses in systemic lupus. Kidney Int. 89(1):158-66
(2015) Reactivity to the p305 Epitope of the α1G T-Type Calcium Channel and Autoimmune-Associated Congenital Heart Block. J Am Heart Assoc.
Figgett WA et al 2015 Deleting the BAFF receptor TACI protects against systemic lupus erythematosus without extensive reduction of B cell numbers. J Autoimmun. 61:9-16
Tan Y et al 2015 Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells. J Immunol. 194(1):101-12
Tonello M et al 2015 Plasma exchange effectively removes 52- and 60-kDa anti-Ro/SSA and anti-La/SSB antibodies in pregnant women with congenital heart block. Transfusion. Epub
Al Kindi MA et al, 2015 Serum SmD autoantibody proteomes are clonally restricted and share variable-region peptides. J Autoimmun. 57:77-81
(2015) Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome. J Exp Med. 212(10):1663-77
(2015) Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL. Blood. 125(10):1578-88
Watkins AA, Bonegio RG and Rifkin IR 2014 Evaluating the role of nucleic acid antigens in murine models of systemic lupus erythematosus. Methods Mol Biol. 1169:143-58
Hamelin-Peyron C et al 2014 Prostate cancer biomarker annexin A3 detected in urines obtained following digital rectal examination presents antigenic variability. Clin Biochem. 47(10-11):901-8
Croca S et al 2014 Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study. Arthritis Res Ther. 16(1):R48
Favoino E et al 2014 Effects of adjuvants for human use in systemic lupus erythematosus (SLE)-prone (New Zealand black/New Zealand white) F1 mice. Clin Exp Immunol. 175(1):32-40
Jackson SW et al 2014 Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation. J Immunol. 192(10):4525-32
De Salort J et al 2013 Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens. Front Immunol. 4:225
Volchenkov R et al 2013 In vitro suppression of immune responses using monocyte-derived tolerogenic dendritic cells from patients with primary Sjögren's syndrome. Arthritis Res Ther. 15(5):R114
Szittner Z et al 2013 Application of fluorescent monocytes for probing immune complexes on antigen microarrays. PLoS One. 8(9):e72401
Wiedeman AE et al, 2013 Contrasting mechanisms of interferon-α inhibition by intravenous immunoglobulin after induction by immune complexes versus Toll-like receptor agonists. Arthritis Rheum. 65(10):2713-23
Thurgood LA et al, 2013 An immunodominant La/SSB autoantibody proteome derives from public clonotypes. Clin Exp Immunol. 174(2):237-44
Giltiay NV et al 2013 Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells. J Exp Med. 210(12):2773-89
Aqrawi LA et al, 2013 Ro52- and Ro60-specific B cell pattern in the salivary glands of patients with primary Sjögren's syndrome. Clin Exp Immunol. 172(2):228-37
Hayman MW et al 2013 Biotinylation of ANCA target antigen improves assay performance for PR3-ELISA but not MPO-ELISA. Pathology. 45(5):525-7
Ernst PB et al 2012 Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice. Am J Physiol Gastrointest Liver Physiol. 302(1):G105-15
Zoega M et al 2012 Proteinase 3 carries small unusual carbohydrates and associates with αlpha-defensins. J Proteomics. 75(5):1472-85
Arentz G et al 2012 Secreted human Ro52 autoantibody proteomes express a restricted set of public clonotypes. J Autoimmun. 39(4):466-70
Shin MS et al, 2012 U1-small nuclear ribonucleoprotein activates the NLRP3 inflammasome in human monocytes. J Immunol. 188(10):4769-75
Wheeler TT et al, 2011 The BPI-like/PLUNC family proteins in cattle. Biochem Soc Trans. 39(4):1006-11
Lindop R et al, 2011 Molecular signature of a public clonotypic autoantibody in primary Sjögren's syndrome: a "forbidden" clone in systemic autoimmunity. Arthritis Rheum. 63(11):3477-86
Schneider Z et al 2011 Transgenic expression of bovine neonatal Fc receptor in mice boosts immune response and improves hybridoma production efficiency without any sign of autoimmunity. Immunol Lett. 137(1-2):62-9
Nixon G et al 2011 Streptokinase antibodies in patients presenting with acute coronary syndrome in three rural New Zealand populations. J Clin Pathol. 64(5):426-9
Santer DM et al 2010 C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes. J Immunol. 185(8):4738-49
Demaria O et al, 2010 TLR8 deficiency leads to autoimmunity in mice. J Clin Invest. 120(10):3651-62
Ting YT et al 2010 Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection. Transplantation. 89(9):1071-8
Summers SA et al, 2010 TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy. J Autoimmun. 35(4):291-8
Kubota T et al, 2009 Possible involvement of chemokine-induced platelet activation in thrombophilic diathesis of antiphospholipid syndrome. Ann N Y Acad Sci. 1173:137-45
Heidari Y et al 2009 A lupus-susceptibility C57BL/6 locus on chromosome 3 (Sle18) contributes to autoantibody production in 129 mice. Genes Immun. 10(1):47-55
Santer DM et al, 2009 Potent induction of IFN-alpha and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus. J Immunol. 182(2):1192-201
Uccellini MB et al 2009 Toll-like receptor-dependent immune complex activation of B cells and dendritic cells. Methods Mol Biol. 517:363-80
Dähnrich C et al 2009 New ELISA for detecting primary biliary cirrhosis-specific antimitochondrial antibodies. Clin Chem. 55(5):978-85
Ramanujam M et al, 2009 Interferon-alpha treatment of female (NZW x BXSB)F(1) mice mimics some but not all features associated with the Yaa mutation. Arthritis Rheum. 60(4):1096-10
Hase K et al 2008 Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease. PLoS One. 3(8):e3033
Kim D et al 2008 Induction of interferon-alpha by scleroderma sera containing autoantibodies to topoisomerase I: association of higher interferon-alpha activity with lung fibrosis. Arthritis Rheum. 58(7):2163-73
Reed JH, Jackson MW and Gordon TP 2008 A B cell apotope of Ro 60 in systemic lupus erythematosus. Arthritis Rheum. 58(4):1125-9
Kahn P et al, 2008 Prevention of murine antiphospholipid syndrome by BAFF blockade. Arthritis Rheum. 58(9):2824-34
McBride JD et al 2008 Screening autoantibody profiles in systemic rheumatic disease with a diagnostic protein microarray that uses a filtration-assisted nanodot array luminometric immunoassay (NALIA). Clin Chem. 54(5):883-90
O’Donnell JL et al, 2007 Antineutrophil cytoplasmic antibody measurement: advantages and disadvantages of a capture PR3 ELISA and a direct PR3 ELISA. Pathology. 39(2):258-63
Pang S et al, 2005 A comparability study of the emerging protein array platforms with established ELISA procedures. J Immunol Methods. 302(1-2):1-12
Lin JL et al, 2005 Major immunoreactive domains of human ribosomal P proteins lie N-terminal to a homologous C-22 sequence: application to a novel ELISA for systemic lupus erythematosus. Clin Exp Immunol. 141(1):155-64
Baiu et al, 2005 Autoantibodies to vascular smooth muscle are pathogenic for vasculitis. Am J Pathol. 166(6):1851-60
Pang S et al, 2005 Relative quantification of experimental data from antigen particle arrays. Clin Chem. 51(6):1029-31
Lau CM et al 2005 RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J Exp Med. 202(9):1171-7
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